Brain Tumors 2016: From Biology to Therapy

DAY 1 Monday, 27 June
08:00 - 09:00 Registration and welcome coffee
09:00 - 09:10 Opening remarks
09:10 - 12:50 Origins of brain tumors and glioblastoma heterogeneity (chairs: Dolores Hambardzumyan, Bozena Kaminska)
09:10 - 10:00   Keynote lecture: Colin Watts - Surgical strategies to interrogate the genomics of glioblastoma
University of Cambridge, UK
10:00 - 10:40   Dominik Sturm - Molecular characterization of CNS primitive neuroektodermal tumors
University Hospital Heidelberg and German Cancer Research Center, Germany
10:40 - 11:10 COFFEE BREAK
11:10 - 11:50   Lene Uhrbom - A cell of origin - based strategy to decipher glioblastoma biology
University of Uppsala, Sweden
11:50 - 12:30   Simone Niclou - Resolving genetic and phenotypic heterogeneity in glioblastoma
Luxemburg Institute of Health, Luxemburg
12:30 - 13:10   Benjamin Deneen - Identification of diverse astrocytic populations and their emergence during glioma induced seizures
Baylor College of Medicine, Houston, USA
13:10 - 14:00 Lunch break and sponsored lecture Adam Olejnik - SeqCap EZ MedExome Target Enrichment Kit. Coverage with Confidance Roche Diagnostics Polska
14:00 - 17:20 Brain tumor therapy (chairs: Zvi Cohen, Pawel Nauman)
14:00 - 14:40   Zvi Cohen - Harnessing nanomedicine as a new approach for  GBM treatment
Sheba Medical Center, Tel Ashomer, Israel
14:40 - 15:20   Geoffrey Pilkington - A role for new therapeutic targets and re-purposed/re-formulated drugs in glioma therapy
University of Portsmouth, UK
15:20 - 16:00   Joan Seoane - Glioblastoma microenvironment
Vall d’Hebron Institute of Oncology, Spain
16:00 - 16:30 COFFEE BREAK
16:30 - 17:10   Oral presentations selected from submitted abstracts
•    Susan Brandenburg - In human GBM, the pro-angiogenic phenotype of microglia/macrophages depends on the infiltration rate of granulocytes
Charité - Universitätsmedizin Berlin, Germany
•    Roland E. Kälin - Apelin signaling controls glioblastoma neo-vascularization and growth
University Clinics, LMU Munich, Germany
•    Dominika Pszczolkowska - Tumor-derived osteopontin via its RGD motif is responsible for the protumorigenic reprogramming of glioma- infiltrating microglia/macrophages and glioma growth
Nencki Institute of Experimental Biology, Poland
17:10 - 17:50   Rolf Bjerkvig - Identifying new drugs for primary and secondary brain tumours using cMap
University of Bergen, Norway
18:30 - 21:00 Welcome reception at Staszic Palace (Palac Staszica, Nowy Świat 72, Warsaw)
     
DAY 2 Tuesday, 28 June
09:00 - 12:20 Signaling in brain tumors (chairs: Lene Uhrbom, Aleksandra Ellert-Miklaszewska)
09:00 - 09:50   Keynote lecture: Daniel J. Brat - A contemporary molecular view of diffuse gliomas with implications for diagnosis
Winship Cancer Institute of Emory University, Atlanta, USA
09:50 - 10:30   Ksenya Shchors - Combinatorial therapy design in glioblastoma models
Swiss Federal Institute of Technology, Switzerland
10:30 - 11:00 COFFEE BREAK
11:00 - 11:40   Etty (Tika) Benveniste - Role of CK2 in GBM and autoimmunity
University of Alabama, Birmingham, USA
11:40 - 12:20   Bozena Kaminska - Glioma-derived osteopontin/SPP1 supports glioma stem-like cells and blocks anti-tumor responses
Nencki Institute, Warsaw, Poland
12:20 - 13:10 LUNCH
13:10 - 17:00 Glioma immunology and immunotherapy (chairs: Tika Benveniste, Katarzyna Kotulska)
13:10 - 13:50   Duane Mitchell - Cellular immunotherapy targeting malignant gliomas
University of Florida, USA
13:50 - 14:30   Dolores Hambardzumyan - The role of pro-inflammatory chemokine network in gliomagenesis
Emory University School of Medicine, Atlanta, USA
14:30 - 15:10   Christel Herold-Mende - Immunological changes during tumor progression from primary to recurrent glioblastoma
University Hospital Heidelberg, Germany
15:10 - 15:40 COFFEE BREK
15:40 - 16:20   Michael Platten - Targeting IDH1R132H for glioma immunotherapy
University Hospital Heidelberg and German Cancer Research Center, Germany
16:20 - 17:00   Gaetano Finocchiaro - Glioblastoma immunotherapy 
IRCCS Foundation "C. Besta" Neurological Institute, Milan, Italy
17:00 - 19:00 Poster session (wine and cheese by the posters)
20:00 - 23:00 Gala dinner (by invitation)
     
DAY 3 Wednesday, 29 June
09:00 - 14:10 Glioma signaling and biology (chairs: Frank AE Kruyt, Cristina Limatola)
09:00 - 09:40   Keynote lecture: Katarzyna Kotulska - mTOR inhibitors in tuberous sclerosis: from brain tumor  treatment to the control of systemic disease
The Children’s Memorial Health Institute, Poland
09:40 - 10:20   Monika Hegi - Epigenetic Deregulation in Glioma, Biomarkers and New Opportunities
University Hospital Lausanne, Switzerland
10:20 - 11:00   Steven Rosenfeld - Molecular motors are drivers of proliferation and invasion in glioblastoma
Cleveland Clinic, USA
11:00 - 11:30 COFFEE BREAK
11:30 - 12:10   Frank AE Kruyt - Differentiation and invasion in glioblastoma
University of Groningen, Netherlands
12:10  -12:50   Cristina Limatola - Environmental and pharmacological tools to reprogram microglia/macrophages infiltrating brain tumor
Sapienza University, Rome, Italy
12:50 - 13:30   Jacek Jaworski - Tuberous Sclerosis Complex neuropathology requires glutamate-cysteine ligase
International Institute of Molecular and Cellular Biology, Warsaw, Poland
13:30 - 14:10 Farewell lunch
14:15 - Guided tour: Warsaw sightseeing