Brain Tumors 2018: From Biology to Therapy
| DAY 1 Thursday, 21 June | ||
| 11:00 - 13:00 | Registration and welcome coffee | |
| 13:00 - 14:00 | Keynote lecture: Luis F. Parada (Memorial Sloan Kettering Cancer Center, New York, USA) The role of cell of origin and cancer stem cells in GBM Phenotype |
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| 14:00 - 17:50 | Brain tumor pathobiology and diagnostics (chairs: Dolores Hambardzumyan, B. Kaminska) | |
| 14:00 - 14:40 | Dinorah Friedmann-Morvinski (Tel Aviv University, Israel) Cell state reprogramming and oncogene-induced plasticity in glioblastoma |
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| 14:40 - 15:20 | Gabriele Bergers (University of Leuven, Leuven, Belgium) Glioma heterogeneity in space and time |
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| 15:20 - 16:00 | Katrin Lamszus (Universitätsklinikum Hamburg-Eppendorf; Hamburg, Germany) Single cell tracking analysis of the clonal architecture and clonal immunoediting in gliomas using optical barcoding |
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| 16:00 - 16:30 | COFFEE BREAK | |
| 16:30 - 17:10 | William Leenders (Radboud University Medical Centre, Nijmegen, Netherlands) Quantitative targeted next generation RNA sequencing to identify aberrant biology in glioma: its value for molecular diagnosis, prognosis and personalized therapy predictions |
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| 17:10 - 17:50 | Geoffrey J. Pilkington (Brain Tumour Research Centre, University of Portsmouth, UK) Three dimensional human in vitro models pave the way for drug delivery and fast tracking of repurposed and reformulated drugs to clinic in neuro-oncology |
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| 18:00 - 21:00 | WELCOME RECEPTION | |
| DAY 2 Friday, 22 June | ||
| 09:00 - 17:30 | Glioma immunology and immunotherapy (chairs: Christel Herold-Mende, Aleksandra Ellert-Miklaszewska) | |
| 09:00 - 09:40 | Helmut Kettenmann (Max Delbruck Center, Berlin, Germany) Mechanisms of microglia/brain macrophage interaction with glioma |
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| 09:40 - 10:20 | Bozena Kaminska (Nencki Institute, Warsaw, Poland) Targeting glioma-microglia communication |
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| 10:20 - 10:50 | COFFEE BREAK | |
| 10:50 - 11:30 | Bjarne Winther Kristensen (University of Southern Denmark, Odense, Denmark) Tumor associated microglia/macrophages in gliomas - a critical player in the tumor microenvironment |
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| 11:30 - 12:10 | Dolores Hambardzumyan (Emory University, School of Medicine, Atlanta, USA) Genetic driver mutations and immune microenvironment in GBM |
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| 12:10 - 12:50 | Christel Herold-Mende (University of Heidelberg, Germany) T cell target antigens and immunobiology of gliomas |
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| 12:50 - 13:50 | LUNCH | |
| 13:50 - 14:30 | Michael Platten (University Hospital Heidelberg and German Cancer Research Center, Germany) Determinants of response to checkpoint blockade in glioma |
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| 14:30 - 15:10 | Simone Niclou (NorLux Neuro-Oncology Laboratory, Luxembourg Institute of Health, Luxembourg) Stem cell-associated heterogeneity in glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment |
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| 15:10 - 15:40 | COFFEE BREAK | |
| 15:40 - 16:10 | Chay T. Kuo (Duke University School of Medicine, Durham, USA) Ventricular progenitor cellular plasticity and tumor initiation |
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| 16:10 - 16:50 | Tambet Teesalu (University of Tartu, Tartu, Estonia) Homing peptides for glioma targeting: discovery and applications for precision guided drug delivery |
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| 16:50 - 17:30 | Oral presentations (4 x 10 min) | |
| 17:30 - 19:00 | Poster session (wine and cheese by the posters) | |
| 20:00 - 23:00 | Gala dinner (by invitation) | |
| DAY 3 Saturday, 23 June | ||
| 09:00 - 11:40 | Brain tumor pathobiology and diagnostics (chairs: K. Bankiewicz, M. Zabek ) | |
| 09:00 - 09:40 | Krystof Bankiewicz (University of California, San Francisco, USA) Large and small volume MR-guided therapeutic infusions in recurrent GBM and DIPG |
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| 09:40 - 10:20 | Massimo Squatrito (Spanish National Cancer Research Center, Madrid, Spain) TRKing down novel therapeutic targets in gliomas |
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| 10:20 - 11:00 | Daniel A. Lim (University of California, San Francisco, USA) Long noncoding RNAs (lncRNA) as therapeutic targets in glioma |
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| 11:00 - 11:40 | Tika Benveniste (University of Alabama at Birmingham, USA) Impact of the Microbiome on Therapeutic Efficacy in GBM |
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| 11:40 - 12:00 | COFFEE BREAK | |
| 12:10 - 15:10 | Brain tumor pathobiology and diagnostics (chairs: T. Benveniste, S. Nawrocki) | |
| 12:10 - 12:50 | Maria G. Castro (University of Michigan, USA) Epigenetic reprogramming in mutant IDH1 glioma mediates ATM upregulation and DNA damage response: therapeutic implications |
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| 12:50 - 13:20 | LUNCH | |
| 13:20 - 14:20 | Waldemar Priebe (MD Anderson Cancer Center, University of Texas, Houston, USA) Multitargeted approach to CNS Malignancies |
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| 14:20 - 14:40 | Angela J Waanders The Children’s Brain Tumor Tissue Consortium (Children Hospital in Philadelphia, USA) Current Landscape: CBTTC International Pediatric Brain Tumor Collaborative Research Consortia |
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| 14:40 - 15:10 | Bartosz Wojtas (Nencki Institute/Polish Network for Glioma therapy) Target sequencing of 700 cancer related genes reveals novel targets for glioma therapy |
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| 15:10 - 15:20 | Closing remarks | |
| 15:30 - 19:00 | Guided tour: Warsaw sightseeing (optional free of charge) |
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Session Sponsored by EACR
