DAY 1 Wednesday, June 22, 2022 |
11:00 - 13:00 |
Registration and welcome coffee |
13:00 - 14:00 |
|
Keynote lecture: John de Groot, University of California San Francisco, USA The future of immunotherapy for glioma
|
14:00 - 17:20 |
Brain tumor pathobiology (chairs: Dolores Hambardzumyan, Bozena Kaminska) |
14:00 - 14:35 |
|
Constantinos G. Hadjipanayis, Mount Sinai Icahn School of Medicine, USA MEK pathway inhibition combined with 5-aminolevulinic acid- photodynamic therapy for the treatment of diffuse midline glioma |
14:35 - 15:10 |
|
Martin van den Bent, Erasmus MC Cancer Institute, Netherlands The landscape of clinical trial in glioma: recently completed and ongoing projects |
15:10 - 15:40 |
COFFEE BREAK |
15:40 - 16:15 |
|
Oren Becher, Mount Sinai Icahn School of Medicine, USA Cellular heterogeneity in diffuse midline gliomas |
16:15 - 16:50 |
|
Jacek Majewski, McGill University, Canada Epigenomic landscapes of H3K27M mutant gliomas |
16:50 - 17:20 |
|
Oral presentations (3x10 min)
Rugile Dragunaite, Lithuanian University of Health Sciences, Kaunas, Lithuania Investigation of m6A modified lncRNAs in different grade gliomas
Irati Hervas-Corpion, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA) and Hospital Universitario Puerta del Mar, Cádiz, Spain Implementation of histone H3 variants in the clinical diagnosis of low- and high-grade gliomas
Katarzyna B. Leszczynska, Nencki Institute ,Warsaw, Poland Epigenetic modulation leads to the decrease of H3K27M oncohistone in pediatric high-grade gliomas
|
17:20 - 18:50 |
Poster session |
19:00 - 21:00 |
WELCOME RECEPTION |
|
|
|
DAY 2 Thursday, June 23, 2022 |
09:00 - 12:25 |
Glioma microenvironment, immunology and immunotherapy I (chairs: Christel Herold-Mende, Aleksandra Ellert-Miklaszewska) |
09:00 - 09:35 |
|
Bozena Kaminska, Nencki Institute, Warsaw, Poland Immune microenvironment of glioma at single cell resolution |
09:35 - 10:10 |
|
Dolores Hambardzumyan, Mount Sinai Icahn School of Medicine, USA Glioblastoma subtype-specific heterogeneity of the immune microenvironment |
10:10 - 10:40 |
COFFEE BREAK |
10:40 - 11:15 |
|
Katrin Lamszus,Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Cancer immunoediting in malignant glioma - interactions between immune cells and tumor cells |
11:15 - 11:50 |
|
Dieter Henrik Heiland, University of Freiburg, Germany Spatiotemporal dynamics in the structural immunity of the glioblastoma microenvironment |
11:50 - 12:25 |
|
Christel Herold-Mende, University of Heidelberg, Germany Determinants of immune cell infiltration and immune responses in brain tumors |
12:25 - 13:20 |
LUNCH BREAK
|
13:20 - 18:00 |
Brain tumor microenvironment, immunology and immunotherapy II (chairs: Dinorah Friedman-Morvinski, Wiesława Grajkowska) |
13:20 - 13:55 |
|
Hai-Kun Liu, German Cancer Research Center (DKFZ), Germany Metabolic plasticity and cancer stem cell dormancy in glioblastoma |
13:55 - 14:30 |
|
Alessandro Michelucci, Luxembourg Institute of Health, Luxembourg Revealing and harnessing tumour-associated microglia/macrophage heterogeneity in glioblastoma |
14:30 - 15:05 |
|
Dinorah Friedmann-Morvinski, Tel Aviv University, Israel Boosting CAR-T cell efficacy by modulation of the microenvironment in brain tumors |
15:05 - 15:20 |
|
Sponsored: Agnieszka Ciesielska (Analityk | 10x Genomics) Multiomic tumor microenvironment profiling using single cell and spatial trancriptomic solutions. |
15:20 - 15:45 |
COFFEE BREAK |
15:45 - 16:20 |
|
Houtan Noushmehr, Henry Ford Health, USA Advances in epigenomic classification and liquid biopsy in glioma |
16:20 - 16:55 |
|
Neta Erez, Tel Aviv University, Israel Lipocalin-2 systemic signaling drives neuroinflammation and brain metastasis |
16:55 - 17:30 |
|
Oral presentations (3x10 min)
Lena Jassowicz, Heidelberg University Hospital, Heidelberg, Germany Characterizing the Immune and Stromal Microenvironment of Breast Cancer Brain Metastases
Divsha Sher, Tel Aviv University, Israel Transformation of Oligodendrocytes into Malignant Glioma Results in Cell of Origin-Specific Behavioral Deficits
Aditya Shroff, University College London, UK Molecular profiling of a novel somatic murine mutant-IDH glioma model enables identification of high-risk mutant-IDH astrocytoma patient subgroup
|
20:00 - 23:00 |
Gala dinner (by invitation) |
|
|
|
DAY 3 Friday, June 24, 2022 |
09:00 - 16:00 |
Brain tumor pathobiology, diagnostics & therapy (chairs: Sergiusz Nawrocki) |
09:00 - 09:35 |
|
Itay Tirosh, Weizmann Institute of Science, Israel Intra-tumor heterogeneity and cellular hierarchies in glioma
|
09:35 - 10:10 |
|
Rolf Bjerkvig, University of Bergen, Norway, Luxemburg Institute of Health, Luxembrug Glioma cell invasion: growth patterns and mechanistic insight |
10:10 - 10:40 |
COFFEE BREAK |
10:40 - 11:15 |
|
Guido Reifenberger, Heinrich Heine University of Dusseldorf, Germany Recent advances in the molecular classification of gliomas – The new WHO classification 2021 and beyond |
11:15 - 11:50 |
|
Maria G. Castro, University of Michigan Medical School, USA Epigenetic reprogramming of the tumor immune microenvironment in mutant IDH1 gliomas impacts myelopoiesis and reverses immunosuppression
|
11:50 - 12:05 |
|
Sponsored: Wojciech Bieniek (Perlan) Real-time analysis of cellular function with the Seahorse metabolic analyzer |
12:05-13:05
|
LUNCH BREAK
|
13:05 - 13:40 |
|
Maciej Wiznerowicz, International Institute for Molecular Oncology, Poland
Cancer stemness defined by proteogenomics guides personalized therapies
|
13:40 - 14:15 |
|
Petra Hamerlik, AstraZeneca, UK Functional interplay between aberrant DNA repair and cellular hierarchies in glioblastoma |
14:15 - 14:50 |
|
Agnieszka Bronisz, Mossakowski Medical Research Institute, Poland
Targeting hypoxia response for oncolytic virus immunotherapy
|
14:50 - 15:25 |
|
Waldemar Priebe, MD Anderson Cancer Center, University of Texas, Houston, USA Drug discovery in academia: focus on CNS malignancies |
15:25-16:00 |
|
Glenn Lesser, Wake Forest School of Medicine, USA
Trials and Tribulations: Reimagining Our Clinical Trial Approaches to CNS Malignancies
|
16:00 - 16:10 |
Closing remarks |
16:10 - 19:00
|
Guided tour: Warsaw sightseeing (optional, free of charge) |
 |